South Carolina

FAQs

22 questions listed below address rabies and rabies vaccination laws/regulations. RESPONSES listed for each of the QUESTIONS within the FAQ section of this website have been validated by the State Public Health Authorities in the respective state.

Click on the question(s) below to reveal the state responses.

  1. Rabies vaccination is required for which species?

    • Dogs, cats, and ferrets are required by law to be vaccinated against rabies. 

  2. Who is legally authorized to administer a rabies vaccine?

    • The rabies inoculation for pets must be administered by a licensed veterinarian or someone under a licensed veterinarian's direct supervision, as defined in Section 40 69 20 of SC Code of Law. 

  3. How long must a copy of the signed rabies certificate be maintained by the practice?

    • The licensed veterinarian administering or supervising the administration of the vaccine shall provide one copy of the certificate to the owner of the pet and must retain one copy in his files for not less than three years. [SC also requires annual reporting: Annually before February first, the veterinarian shall report to the department the number of animals inoculated against rabies during the preceding year.] 

  4. What are the age requirements for rabies vaccination in South Carolina?

      • MINIMUM Age: 12 weeks of age

      • MUST BE VACCINATED BY: South Carolina does not stipulate a MUST BE VACCINATED BY age. It does state that: “A pet owner must have his pet inoculated against rabies at a frequency to provide continuous protection of the pet...” 

  5. Following administration of the initial dose of rabies vaccine, when is an animal considered to be "currently vaccinated"?

    • 28 days following administration of the initial dose of rabies vaccine. This applies regardless of the animal’s age at the time the initial dose is administered. 

  6. What criteria constitute "currently vaccinated" against rabies?

    • The term “currently vaccinated” is commonly used within the context of state laws affecting rabies vaccination and control. Within the US, an animal that is “currently vaccinated” must meet EACH of the following criteria.  

      The animal must be vaccinated:

      • ...with a USDA licensed rabies vaccine.

      • ...with a vaccine that is within the labeled expiration date.

      • ...by an individual who is authorized to administer rabies vaccine.
        (NOTE: requirements vary significantly among states-see FAQ #2 for the requirement in this state).

      • ...at the appropriate age, interval, and dose (i.e., the FULL dose, as stipulated on the manufacturer’s label, must be administered). 

  7. Is there an extended-duration (beyond 3 years) rabies vaccine available today? (see also Question #10)

    • NO. 

      USDA licensed rabies vaccines available for administration to animals residing with the US are only 1-Year or 3-Year labeled vaccines. 4-YEAR labeled rabies vaccines have been discontinued and are no longer recognized in the US.  

      In South Carolina, a veterinarian has the discretion to administer a 1-Year or 3-Year labeled rabies vaccine as THE INITIAL DOSE. However...re-vaccination (booster) is required 1 year following the initial dose...regardless of the animal’s age and regardless of the vaccine administered as the initial dose.  

      RE-VACCINATION of DOGS and CATS: When re-vaccinating (booster) against rabies, the duration that a dog or cat is considered “currently vaccinated” is strictly determined by the product label of the last vaccine administered (i.e., either 1 year or 3 years).  

      RE-VACCINATION of FERRETS: When re-vaccinating (booster) against rabies, the duration that a ferret is considered “currently vaccinated” is only 1 year.  

  8. What are the rabies vaccination requirements for a dog/cat imported from another state or country?

    • The State of South Carolina does not list specific ‘import’ requirements related to rabies vaccination of pets (cat, dog, or ferret). 

  9. Can a 3-year labeled rabies vaccine be substituted for a 1-year labeled rabies vaccine when administering the initial dose?

    • South Carolina does not specifically address this issue in law. However, there are no restrictions in doing so. 

      NOTE: regardless of the product used, a dog, cat, and ferret must receive a single booster dose within 1 year following the initial dose to be considered “currently vaccinated” regardless of the product used.  

      Thereafter, the choice of vaccine administered (1-Year or 3-Year) is at the discretion of the licensed veterinarian who administers the vaccine. 

  10. What are the re-vaccination requirements for a pet that is overdue for a required rabies booster? (4 parts)

    • When is an animal considered to be "overdue" for a rabies booster?

      • An animal is considered “overdue”, and NOT currently vaccinated, if just one day beyond the labeled duration of the last rabies vaccine administered (1 year or 3 years).  

        The exception to this rule is that an animal is considered “overdue” after just one year following the initial rabies vaccine dose, regardless of the vaccine labeling.  

    • Following re-vaccination of an "overdue" animal, when is the animal considered to be "currently vaccinated"?

      • A dog or cat that is overdue for a rabies vaccine is considered “immediately currently vaccinated” at the time the animal is re-vaccinated. 

        This rule applies despite the time that has lapsed since administration of the previous dose of rabies vaccine.  

    • When re-vaccinating the “overdue” patient, which vaccine must be used (1-Year or 3-Year labeled vaccine)?

      • Veterinarians in South Carolina have discretion to re-vaccinate the overdue pet with either a 1-Year or a 3-Year labeled rabies vaccine. 

    • When is the NEXT dose due?

      • The time for the next booster dose is determined by the product used, i.e., either 1 year or 3 years. 

  11. Can a "positive" rabies antibody titer substitute for a required booster dose?

    • NO. Within the United States, a “positive” rabies antibody titer is NOT recognized as an index of immunity (or protection) in lieu of vaccination and therefore does NOT substitute for a required vaccination.  

      NOTE: A “positive” rabies titer from a certified laboratory only means that the animal (at the time of travel) has been “adequately vaccinated” against rabies and meets the rabies vaccination requirement of that country/region at the time of importation. 

      For a current list of importation requirements by country see: https://www.aphis.usda.gov/aphis/pet-travel or Search: APHIS Pet Travel 

  12. What constitutes rabies "exposure" in a pet?

    • In South Carolina, rabies statutes address the consequences of rabies exposure but don’t specifically define “exposure” criteria in pets. 

  13. Who has the authority to determine if a pet has been exposed to rabies?

    • State Response Pending

  14. What are the consequences of rabies "exposure" in a pet that is "currently vaccinated"? (see also FAQ #6 and #13)

    • STRICTLY ENFORCED: In South Carolina the county health department shall serve a written notice to the owner of a currently vaccinated pet that has been bitten by or otherwise exposed to any animal affected or suspected of being affected by rabies. The notice must require the owner to have a currently inoculated pet re-vaccinated immediately (within 96 hours of exposure) and to quarantine the pet for a period of not less than forty-five (45) days. 

  15. What are the consequences of rabies "exposure" in a pet that is not "currently vaccinated"? (see also FAQ #6 and #13)

    • Three variations must be considered in determining management of the exposed animal.

      • Unvaccinated (ie, has NEVER been vaccinated against rabies):

        • An unvaccinated pet must be quarantined for a period of not less than one hundred eighty days. The unvaccinated pet must be inoculated after one hundred fifty days of the quarantine period and released from quarantine thirty days after that if no sign of rabies is observed.  

          [In South Carolina, the State Public Health Veterinarian frequently recommends immediate re-vaccination at the beginning of quarantine. Euthanasia is an option in South Carolina, as well.] 

      • Is OVERDUE for a booster, and has documentation of prior vaccination:

        • State Response Pending

      • Is OVERDUE for a booster, but DOES NOT HAVE documentation of vaccination:

        • State Response Pending

  16. Does South Carolina recognize the results of Prospective Serologic Monitoring (PSM) as valid documentation that a dog/cat has been previously vaccinated against rabies?

    • State Response Pending 

      Prospective Serologic Monitoring (PSM) is a defined testing protocol specifically indicated for use in dogs & cats (ONLY) that have been determined (by public health or rabies control authorities) to be “exposed” to rabies (See also FAQs #12 and #13 in this section) yet, the owner is unable to provide valid documentation of recent rabies vaccination.  

      NOTE: the PSM testing protocol and submission requirements are strictly defined and must be adhered to. The PSM testing protocol is available at: http://www.nasphv.org/Documents/NASPHVSerologicMonitoring2016.pdf 

      Indications for PSM: Applies ONLY to dogs and cats. 

      WHERE PSM is ALLOWED BY THE STATE or LOCAL JURISDICTION, all the following criteria must apply:

      • the dog/cat has been exposed to a confirmed or suspected rabid animal (as determined by public health or designated rabies control authorities); and,

      • the owner cannot provide valid documentation of previous vaccination (with a USDA Licensed vaccine); and,

      • the owner of the dog/cat that is determined to have been “exposed” to rabies (see questions #12 and #13) wants to avoid euthanasia or the expense of strict quarantine (usually 4 months or 6 months, depending on the state); and,

      • the animal can be managed by a veterinarian who is able to conduct the PSM protocol.

    • NOTE: Please check the National Association of State Public Health Veterinarians website at www.nasphv.org for the most current guidance on the testing protocol prior to any sample collection. 

      NOTE: properly labelled, paired specimens are required. Do not send samples separately. Both serum samples should be received by the laboratory at the same time. 

  17. What action is required if an animal that is "currently vaccinated" bites a person? (see also FAQ #6)

    • The animal causing a bite injury to a person is required to be quarantined for 10 DAYS. 

      DO NOT VACCINATE the animal prior to beginning the 10-day confinement.  

      REASON: an adverse reaction to the vaccine could be confused with early signs of rabies and could result in a decision to euthanize and test. 

      NOTE: This requirement is the same whether the biting animal is currently vaccinated or is not vaccinated. See FAQ #18.  

      (NOTE: THE LOCATION IN WHICH THE ANIMAL IS QUARANTINED MAY BE DETERMINED BY LOCAL RABIES CONTROL AUTHORITIES). 

  18. What action is required if an animal that is "not currently vaccinated" bites a person? (see also FAQ #6)

    • The animal causing a bite injury to a person is required to be quarantined for 10 DAYS. 

      DO NOT VACCINATE the animal prior to beginning the 10-day confinement.  

      REASON: an adverse reaction to the vaccine could be confused with early signs of rabies and could result in a decision to euthanize and test. 

      NOTE: This requirement is the same whether the biting animal is currently vaccinated or is not vaccinated. See FAQ #18.  

      (NOTE: THE LOCATION IN WHICH THE ANIMAL IS QUARANTINED MAY BE DETERMINED BY LOCAL RABIES CONTROL AUTHORITIES). 

  19. As a licensed veterinarian, do you have the authority to exempt an animal from the legal requirement to be vaccinated against rabies? (eg., for medical reasons)

    • No. This is firm. Furthermore, local municipalities are not authorized to grant such exemptions. 

  20. At what age is it no longer necessary to vaccinate an animal against rabies?

    • Within states that require rabies vaccine be administered, re-vaccination is required throughout life at the appropriate interval for the species as required by State or local laws/regulations. Exemption is not authorized on the basis of age. 

  21. Is rabies vaccination of a hybrid or exotic pet allowed or recognized?

    • In South Carolina, vaccination of hybrid animals against rabies does NOT constitute immunization or the animal being “currently vaccinated” since none of the current USDA licensed rabies vaccines are labeled for use in hybrid species. Hybrid pets are considered “wild animals” in the event of exposure or in the event a person is bitten by a hybrid pet. 

      If a hybrid pet is considered to be ‘exposed’ to rabies or bites a person, quarantine is NOT an option. The animal will be euthanized and may be tested for rabies. 

  22. At the State level, what authority does the Compendium of Animal Rabies Prevention and Control carry?

    • The Compendium of Animal Rabies Prevention and Control is published by the National Association of State Public Health Veterinarians, Inc. Recommendations outlined in the latest version of the Compendium serve as a basis for animal rabies prevention and control programs throughout the United States and facilitate standardization of procedures among jurisdictions. As published, the Compendium is not a statutory document. 

      NOTE: many (but not all) States have recently revised rabies laws/regulations by citing designated recommendations outlined in the latest version of the Compendium. Where cited in law, published recommendations do serve as the legal basis for patient management decisions made in practice as they concern rabies and rabies vaccination.  

      Compendium recommendations, if included as legal requirements for this state, are reflected in the FAQs listed within this section.  

South Carolina

Public Health Contact

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*State Validation Pending

DHEC BEHS Headquarters

Phone: 803-896-0640
Fax: 803-896-0645

Rabies Control Staff
Phone: 803-896-0655
Fax: 803-896-0645

State Public Health Veterinarian
(Position is Currently Vacant)

South Carolina Dept. of Health and Environmental Control
Director, Surveillance and Outbreak Investigation Section
Division of Acute Disease Epidemiology
2100 Bull Street
Columbia, SC 29201

Phone: 803-898-0568
Fax: 803-898-0897

South Carolina

Rabies Surveillance

Confirmed Cases of Rabies in South Carolina

Year 2018 2019 2020 2021
DOMESTIC-TOTAL 19 17 13 11
Dog 1 3 0 3
Cat 15 13 12 7
Ferret 0 0 0 0
WILDLIFE-TOTAL 81 131 155 90
Raccoon* 42 78 86 30

*Primary reservoir host in the state

Rabies surveillance in the United States (2018-2021)
Ma X, et al. From the National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention.
Published in:  Journal of the American Veterinary Medical Association
(2018 data):  256(2):195-208 (Jan 15, 2020)
(2019 data):  258(11):1205-1220 (Jun 1, 2021)
(2020 data):  260(10):1157-1165 (July 2022)
(2021 data): 261(7):1045-1053 (July 2023)

South Carolina

Rabies References

National References
  1. Compendium of Animal Rabies Prevention and Control, 2016. National Association of State Public Health Veterinarians, Inc. JAVMA March 1, 2016. Vol 248. No 5, pp. 505-517. Click here to view online.
  2. Rabies: a neglected zoonotic disease. World Health Organization. 2013. Click here to view online.
  3. Compendium of Animal Rabies Prevention and Control, 2011. National Association of State Public Health Veterinarians, Inc. Released May 31, 2011. Click here to view online.
  4. Wasik B and Murphy M. RABID A Cultural History of the World’s Most Diabolical Virus. Viking (Penguin Group), New York, 2012.
  5. The Rabies Laboratory, College of Veterinary Medicine, Kansas State University. Click here to view online.
  6. Greene CE. Rabies and other Lyssavirus infections. Chapt 20 in CE Greene (ed): Infectious Diseases of the Dog and Cat. 4th Ed. Elsevier-Saunders, St. Louis, 2012, pp. 179-197.